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Allergen Gal d 4(46-61),chicken(Lysozyme C(46-61)(chicken))
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:62982-31-4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Allergen Gal d 4 (46-61), chicken (Lysozyme C (46-61) (chicken)) 是一种鸡蛋清溶菌酶肽。
Cas No.62982-31-4
别名Lysozyme C (46-61) (chicken)
Canonical SMILESAsn-Thr-Asp-Gly-Ser-Thr-Asp-Tyr-Gly-Ile-Leu-Gln-Ile-Asn-Ser-Arg
分子式C72H116N22O29
分子量1753.82
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.

Allergen Gal d 4 (46-61), chicken (HEL(46-61)) contains the immunodominant epitope recognized by mice of the k haplotype. The binding is shown to be specific, with a Kd of approximately 2 uM. The direct binding of a hen egg white lysozyme peptide, Allergen Gal d 4 (46-61), is examined to membrane I-Ak (protein encoded in the A locus of the I region) molecules in the presence of detergent. A number of synthetic peptide derivatives, which do not stimulate our T-cell reactive hybridomas, compete for the binding of Allergen Gal d 4 (46-61) to I-Ak and also inhibit the functional presentation of Allergen Gal d 4 (46-61). Inhibitors include a peptide lacking a tyrosine at position 53 and a peptide corresponding to the autologous lysozyme peptide. Presentation is examined with cells or with supported planar phospholipid membranes bearing only I-Ak and Allergen Gal d 4 (46-61)[1].

[1]. Proc Natl Acad Sci U S A. 1986 Jun;83(12):4509-13.