| CAS NO: | 58579-51-4 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1g | 电议 |
| Molecular Weight (MW) | 292.55 |
|---|---|
| Formula | C10H7Cl2N3O.HCl |
| CAS No. | 58579-51-4 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 14 mg/mL (47.9 mM) |
| Water:<1 mg/mL | |
| Ethanol: <1 mg/mL | |
| Other info | Chemical Name: Imidazo(2,1-b)quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, monohydrochloride InChi Key: TVWRQCIPWUCNMI-UHFFFAOYSA-N InChi Code: InChI=1S/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;/h1-2H,3-4H2,(H,13,14,16);1H SMILES Code: O=C1NC2=NC3=C(C(Cl)=C(Cl)C=C3)CN2C1.[H]Cl |
| Synonyms | BL-4162A; Anagrelide hydrochloride; BL 4162A; BL-4162A; BL4162A; Agrylin; Xagrid; GALE-401; Thromboreductin |
| In Vitro | In vitro activity: Anagrelide is an oral imidazoquinazoline agent with an anti-cyclic AMP phosphodiesterase activity and inhibits platelet aggregation in both humans and animals. Anagrelide works by inhibiting the maturation of platelets from megakaryocytes. Cell Assay: Anagrelide is an established platelet-reducing drug. Studies have also investigated the effects of anagrelide on platelets, indicating that platelet function is as important as platelet counts in ET |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Semin Thromb Hemost. 1997;23(4):379-83; N Engl J Med. 1988 May 19;318(20):1292-4. |
m.cnreagent.com