Lexithromycin 是一种红霉素 A 衍生物,具有抗菌活性。
Cas No. | 53066-26-5 |
别名 | 来红霉素; Erythromycin A 9-methoxime; Wy 48314 |
化学名 | erythromycin, 9-(O-methyloxime) |
Canonical SMILES | C[C@H]1[C@H](O)[C@@](OC)(C)C[C@@](O[C@H]([C@@H](C)C(O[C@H](CC)[C@]([C@H](O)[C@H]/2C)(O)C)=O)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@](C)(O)C[C@@H](C)C2=N/OC)([H])O1 |
分子式 | C38H70N2O13 |
分子量 | 763 |
溶解度 | DMSO: 10 mM |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Lexithromycin is a semi-synthetic antibiotic derived from erythromycin . Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued. |