| Cas No. | 41692-24-4 |
| 化学名 | 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-10,13E-dien-1-oic acid |
| Canonical SMILES | CCCCC(C)(C)C(O)\C=C\[C@H]1C=CC(=O)C1CCCCCCC(=O)O |
| 分子式 | C22H36O4 |
| 分子量 | 364.5 |
| 溶解度 | DMF: >75 mg/ml (from PGA1),DMSO: >50 mg/ml (from PGA1),Ethanol: >100 mg/ml (from PGA1),PBS pH 7.2: >2.4 mg/ml (from PGA1) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 16,16-dimethyl PGA1 is a metabolism resistant analog of PGA1. In vitro, it inhibits the viral replication in both HSV and HIV-1 infection systems at concentrations that do not adversely alter cellular DNA synthesis. The ID50 for HSV-1 strains in Vero cells and human foreskin fibroblasts are 3.8-5.6 ug/ml and 4.6-7.3 ug/ml, respectively. The ID50 for T cells acutely infected with HIV-1 is 2.5 ug/ml. |
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