CAS NO: | 824958-12-5 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 824958-12-5 |
化学名 | (R)-6-(4-(2-(methylthio)phenyl)piperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide hydrochloride |
Canonical SMILES | O=C(CCCCCN1CCN(C2=CC=CC=C2SC)CC1)N[C@@H]3CCCC4=CC=CC=C34.Cl |
分子式 | C27H37N3OS.HCl |
分子量 | 488.13 |
溶解度 | 10mg/mL in ethanol, or in DMSO, or in DMF |
储存条件 | Desiccate at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | LP44 is a full agonist of the serotonin 5-HT7 receptor (Ki = 0.22 nM) that displays 200- and greater than 1,000-fold selectivity over 5-HT1A (Ki = 52.7 nM) and 5-HT2A (Ki = 326 nM) receptors, respectively.1 It can induce relaxation of substance P-induced guinea pig ileum contraction with an EC50 value of 2.56 μM.[1] Reference: |