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hCAII-IN-9
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
hCAII-IN-9图片
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
hCAII-IN-9 是一种强效的碳酸酐酶抑制剂,IC50分别为 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII)。hCAII-IN-9 没有血脑屏障透过性。
生物活性

hCAII-IN-9 is a potentcarbonic anhydrase inhibitor withIC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability[1].

IC50& Target[1]

hCA II

1.18 μM (IC50)

hCA IX

0.17 μM (IC50)

hCA XII

2.99 μM (IC50)

体外研究
(In Vitro)

hCAII-IN-9 (compound 11) (100 μM; 24-48 h) inhibits BHK-21 and HEK-293 cells with cell viability rates of 48% and 72%[1].

体内研究
(In Vivo)

hCAII-IN-9 (compound 11) has no blood-brain barrier permeability[1].

分子量

417.89

Formula

C15H16ClN3O5S2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.