Vinpocetine-d5 is the deuterium labeled Vinpocetine. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na⁺channels. TheIC₅₀value of Vinpocetine on directIKKinhibition in the cell-free system is 17.17 μM. Vinpocetine is aphosphodiesterase (PDE)inhibitor and inhibitsNF-κB-dependent inflammatory responses by directly targetingIκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

355.48

C₂₂H₂₁D₅N₂O₂

2734920-39-7

长春西汀 d5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.