Lenalidomide-propargyl-C2-NH2 hydrochloride 结合了 E3 泛素连接酶的配体 cereblon (CRBN) 和一个 linker。Lenalidomide-propargyl-C2-NH2 hydrochloride 可用于设计 PROTAC MD-224。
| 生物活性 | Lenalidomide-propargyl-C2-NH2 hydrochloride incorporates acereblon(CRBN) ligand for the E3 ubiquitin ligase, and a linker. Lenalidomide-propargyl-C2-NH2 hydrochloride can be used to design thePROTACMD-224 (HY-114312)[1]. |
| IC50& Target[1] | |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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