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Dehydroascorbic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dehydroascorbic acid图片
CAS NO:490-83-5
包装:50mg
市场价:315元

产品介绍
Dehydroascorbicacid,一种可透过血脑屏障的维生素C氧化型,对中风具有有效的脑保护作用。
Cas No.490-83-5
别名脱氢抗坏血酸
Canonical SMILESOC[C@@H]([C@](O1)([H])C(C(C1=O)=O)=O)O
分子式C6H6O6
分子量174.11
溶解度DMSO: 10 mg/ml,DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.

Neuronal injury in ischemic stroke is partly mediated by cytotoxic reactive oxygen species. Although the antioxidant ascorbic acid (AA) or vitamin C does not penetrate the blood-brain barrier (BBB), its oxidized form, dehydroascorbic acid (DHA), enters the brain by means of facilitative transport[1].

[1]. Huang J, et al. Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potentcerebroprotection in experimental stroke. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11720-4.