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1-Methyladenine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1-Methyladenine图片
CAS NO:5142-22-3
包装:5mg
市场价:1071元

产品介绍
1-Methyladenine是DNA中烷基化损伤的产物,可以通过氧化去甲基化的损伤逆转来修复。
Cas No.5142-22-3
别名1-甲基腺嘌呤
Canonical SMILESNC1=C2N=CN=C2N=CN1C
分子式C6H7N5
分子量149.15
溶解度Water: 5.2 mg/mL (34.86 mM; ultrasonic and warming and heat to 80℃)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.

[1]. Falnes P?, et al. Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins. Nucleic Acids Res. 2004 Dec 1;32(21):6260-7. Print 2004. [2]. Yang H, et al. Effect of 1-methyladenine on double-helical DNA structures. FEBS Lett. 2008 May 14;582(11):1629-33.