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5-Hydroxymethyluracil
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-Hydroxymethyluracil图片
CAS NO:4433-40-3
包装:1g
市场价:446元

产品介绍
5-Hydroxymethyluracil是氧化性DNA损伤的产物。5-Hydroxymethyluracil可用作增强或抑制细菌RNA聚合酶转录的潜在表观遗传标记。
Cas No.4433-40-3
别名5-羟甲基脲嘧啶
Canonical SMILESO=C1NC(C(CO)=CN1)=O
分子式C5H6N2O3
分子量142.11
溶解度DMF: 60 mg/ml,DMSO: 53 mg/ml,Ethanol: 0.8 mg/ml,PBS (7.2): 8 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase.

[1]. Djuric Z, et al. Quantitation of 5-(hydroxymethyl)uracil in DNA by gas chromatography with mass spectral detection. Chem Res Toxicol. 1991 Nov-Dec;4(6):687-91. [2]. Janou?ková M, et al. 5-(Hydroxymethyl)uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chem Commun (Camb). 2017 Dec 12;53(99):13253-13255.